Nateglinide is an insulin secretagog agent that lowers blood glucose levels by stimulating insulin secretion from the pancreas. It achieves this by closing ATP-dependent potassium channels in the membrane of theβ cells. This depolarizes the β cells and causes voltage-gated calcium channels to open. The resulting calcium influx induces fusion of insulin-containing vesicles with the cell membrane, and insulin secretion occurs.An amino-acid derivative that stimulates insulin secretion Nateglinide is an insulin secretagog agent that lowers blood glucose levels by stimulating insulin secretion from the pancreas. It achieves this by closing ATP-dependent potassium channels in the membrane of theβ cells. This depolarizes the β cells and causes voltage-gated calcium channels to open. The resulting calcium influx induces fusion of insulin-containing vesicles with the cell membrane, and insulin secretion occurs. An amino-acid derivative that stimulates insulin secretion
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Nateglinide
Dangerous GoodsCAS number：105816-04-4 molecular formula：C19H27NO3
overview
compound introduction
Specs
| Chinese alias | 那格列奈 | ||
| English alias | AKOS000268454 | DJN 608 | HY-B0422 | Nateglinide (Starlix) | Nateglinide impurity C [EP] | NATEGLINIDE [MI] | NC00148 | SCHEMBL303827 | 2,6-Diamino-4(3H)-pyrimidinone | n-(trans-4-Isopropylcylolohexylcarboxyl)-d-phenylpropylicacid | NSC-4918 | NSC-758695 | ||
| CAS number | 105816-04-4 | molecular formula | C19H27NO3 |
| molecular weight | 317.43 g/mol | Exact mass | - |
| PSA | 66.400 Ų | logp | 3.200 |
numbering system
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physicochemical properties
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Safety information
WGK Germany：
3
Personal protective equipment：
Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter
RTECS：
SQ7318950
Production methods and uses
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downstream information
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MSDS
Found 1 shareMSDS
105816-04-4 | Nateglinide (200 mg).pdf
