(S)-(-)-α,α-二苯基-2-吡咯烷甲醇是一种双功能有机催化剂。 应用 (S)-(-)-α,α-二苯基-2-吡咯烷乙醇 (DPPM) 可用于以下过程：DPPM 与儿茶酚硼烷反应生成螺硼酸酯，它可以成为苯乙酮硼烷还原合成对映体纯醇的高效催化剂。二苯甲酮与硼烷-二乙基苯胺原位反应生成的催化剂，能有效地催化 2′ 的对映选择性还原-氟苯乙酮。用 DPPM 功能化的介孔 SBA-15 硅胶可以催化二乙基锌与苯甲醛加成形成 (S)-1-苯基-丙醇。用于制备对应的噁唑硼烷，噁唑硼烷可用于酮的硼烷介导不对称还原反应。 (S)-(-)-α,α-Diphenyl-2-pyrrolidinemethanol is a bifunctional organocatalyst.Used to prepare the corresponding oxazaborolidines for the borane-mediated asymmetric reduction of ketones.(S)-(-)-α,α-Diphenyl-2-pyrrolidinemethanol (DPPM) may be used in the following processes:DPPM reacts with catecholborane to form a spiroborate ester, which can be an efficient catalyst for the synthesis of enantiopure alcohols by borane reduction of acetophenone.The catalyst generated in situ by reacting DPPM with borane-diethylaniline, can efficiently catalyze the enantioselective reduction of 2′-fluoroacetophenone.Mesoporous SBA-15 silica functionalized with DPPM can catalyze the addition of diethylzinc to benzaldehyde to form (S)-1-phenyl-propanol.
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(S)-(−)-α,α-Diphenyl-2-pyrrolidinemethanol
Dangerous GoodsCAS number：112068-01-6 molecular formula：C17H19NO
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | SCHEMBL239738 | (S)-Diphenyl(pyrrolidin-2-yl)methanol | A,A-Diphenyl-L-prolinol | (S)-alpha,alpha-diphenyl-2-pyrrolidine methanol | (S)-alpha,alpha-diphenyl-2-pyrrolidinemethanol | (S)-(-)- alpha , alpha -Diphenyl-2-pyrrolidinemethanol | (S)-(-)-alpha,alp | ||
| CAS number | 112068-01-6 | molecular formula | C17H19NO |
| molecular weight | 253.35 g/mol | Exact mass | - |
| PSA | 32.299 Ų | logp | 2.700 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移
WGK Germany：
3
Personal protective equipment：
dust mask type N95 (US), Eyeshields, Gloves
Production methods and uses
No production method and use information yet
Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
112068-01-6 | (S)-(−)-α,α-Diphenyl-2-pyrrolidinemethanol.pdf
