Application A convergent synthesis of the proposed structure of (+)-pestalazine B has been achieved in 4 steps using the N-alkylation of an unprotected tryptophan diketopiperazine with a 3a-bromopyrrolidinoindoline where the condensation between L-tryptophan methyl ester and N-Fmoc-D-leucine in the presence of EDC as coupling agent afforded the corresponding L-Trp-D-Leu dipeptide.
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Fmoc-D-Leu-OH
Dangerous GoodsCAS number:114360-54-2 molecular formula:C21H23NO4
overview
compound introduction
Specs
| Chinese alias | N-芴甲氧羰基-D-亮氨酸 | N-[(9H-芴-基甲氧基)羰基]-D-亮氨酸 | ||
| English alias | 98ZC4255U2 | AM81874 | CBPJQFCAFFNICX-LJQANCHMSA-N | A803174 | DivK1c_001012 | Spectrum5_001340 | BRD-K65275554-001-03-9 | N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-D-LEUCINE | KBio1_001012 | Spectrum_001482 | (2R)-2-(9H-luoren-9-ylmethoxycarbonylamino)-4-me | ||
| CAS number | 114360-54-2 | molecular formula | C21H23NO4 |
| molecular weight | 353.42 g/mol | Exact mass | ≥98% |
| PSA | 75.600 Ų | logp | 4.400 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入:将人转移
Production methods and uses
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Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
114360-54-2 | Fmoc-D-Leu-OH.pdf





