CAS number：117570-53-3 molecular formula：C17H14O4
5,6-二甲基呫吨酮-4-乙酸（DMXAA）是一种黄酮乙酸衍生物。可作为血管破坏剂（VDA）起作用，破坏肿瘤血管系统并产生抗肿瘤免疫应答。能引起出血性坏死。 用途： 5,6-二甲基呫吨酮-4-乙酸（DMXAA）用于以干扰素基因刺激因子（STING）依赖的方式诱导 I 型 IFN 信号传导。在未感染的情况下，也用于研究 STING 依赖性信号传导。 5,6-dimethylxanthenone-4-acetic acid (DMXAA) is a flavone acetic acid derivative. It acts as a vascular disrupting agent (VDA), which damages tumor vasculature and stimulates an anti-tumor immune response. It stimulates hemorrhagic necrosis. An apoptosis inducer for proteomics research.
| Chinese alias | 2,5-己酮可可碱 | 5,6-二甲基呫吨酮-4-乙酸 | 5,6-二甲基黄嘌呤-4-乙酸 | 2-(5,6-二甲基-9-氧代占吨-4-基)乙酸 | ||
| English alias | ASA404 | 5,6-MeXAA | NSC-640488 | 9H-Xanthene-4-acetic acid, 5,6-dimethyl-9-oxo- | BCPP000255 | J-003637 | 5,6-Mexaa | AC-24559 | NSC-640488 | AS-16852 | DTXSID2040949 | EN300-396606 | NCGC00165783-01 | SW219898-1 | VADIMEZAN [WHO-DD] | (5,6-dimethyl-9-ox | ||
| CAS number | 117570-53-3 | molecular formula | C17H14O4 |
| molecular weight | 282.29 g/mol | Exact mass | - |
| PSA | 63.600 Ų | logp | 3.200 |
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