CAS number：121032-29-9 molecular formula：C11H15N5O5
Nelarabine 一种嘌呤核苷类似物，抑制DNA合成，IC50为0.067-2.15 μM。 Nelarabine (Arranon, 506U78)是嘌呤核苷酸类似物，为DNA合成抑制剂，对肿瘤细胞的IC50为0.067-2.15 μM，可作用于T细胞急性淋巴细胞白血病。 Nelarabine is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells. Nelarabine (arranon, 506U78) is a purine nucleotide analog, which is an inhibitor of DNA synthesis, with an IC50 of 0.067-2.15 for tumor cells μ M. It can act on T cells and acute lymphoblastic leukemia.
| Chinese alias | 奈拉滨 | 9-(β-D-阿拉伯呋喃糖基)-6-甲氧基-9H-嘌呤-2-胺 | 奈拉滨 | ||
| English alias | 506U78 | Arranon | GW 506U78 | Nelzarabine | 9beta-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine | 9-(β-D-Arabinofuranosyl)-6-methoxy-9H-purin-2-amine | (2R,3S,4S,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol | ||
| CAS number | 121032-29-9 | molecular formula | C11H15N5O5 |
| molecular weight | 297.27 g/mol | Exact mass | - |
| PSA | 149.000 Ų | logp | -0.7 |
No numbering system information yet
No physical and chemical property information yet
No production method and use information yet
No upstream information yet
No downstream information yet
