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Vinorelbine ditartrate salt hydrate

Dangerous Goods

CAS number:125317-39-7    molecular formula:C45H54N4O8·2C4H6O6·xH2O

overview

compound introduction

Vinorelbine ditartrate is a selective mitotic microtubule antagonist that exhibits > 20 fold selectivity over axonal microtubules. This compound has been shown to inhibit the proliferation of multiple human tumor cell lines (IC50 = 1.25 nM in HeLa cells). Vinorelbine ditartrate is a selective mitotic microtubule antagonist that exhibits > 20 fold selectivity over axonal microtubules. This compound has been shown to inhibit the proliferation of multiple human tumor cell lines (IC50 = 1.25 nM in HeLa cells).

Specs

Chinese alias长春瑞宾双酒石酸盐 | 重酒石酸长春瑞宾 | KW-2307
English aliasVinorelbine tartrate | 125317-39-7 | Vinorelbine ditartrate | Vinorelbine Bitartrate | 5'-Noranhydrovinoblastine tartrate | Vinorelbine ditartrate salt hydrate | KW-2307;Nor-5'-anhydrovinblastine ditartrate | VinorelbineTartrate | 1217449-57-4 | vinorelbi
CAS number125317-39-7molecular formulaC45H54N4O8·2C4H6O6·xH2O
molecular weight1079.11(dry basis) gExact mass10mM in DMSO
PSA364.000 Ųlogp-

numbering system

No numbering system information yet

physicochemical properties

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Safety information

pictogram:
GHS06 , GHS08 , GHS07
Signal word:
Danger
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H301: 吞咽会中毒 H341: 怀疑引起遗传缺陷 H372: 通过长时间或反复暴露对器官造成损害 H360: 可能损害生育力或未出生的孩子
Statement of Preventive Measures:
P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P281: 根据需要使用个人防护设备。 P270: 使用本产品时,请勿进食、饮水或
WGK Germany:
3
Personal protective equipment:
dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Production methods and uses

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Related

upstream information

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downstream information

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MSDS

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