用于Suzuki-type交叉偶联反应。 应用 4-氰基苯硼酸可作为反应物参与： 钯催化的水相Suzuki-Miyaura交叉偶联。 钌催化无环胺的苄基 sp3 碳与芳基硼酸盐的直接芳基化。 无配体铜催化的硝基芳烃与芳基硼酸的偶联。 高氯酸铁促进富勒烯与各种芳基硼酸的反应，得到富勒烯基硼酸酯。 不含磷的 Suzuki-Miyaura 交叉偶联。 Palladacycles 作为与烯丙基钯中间体的多组分反应的有效催化剂。 Cu催化的硫醇Chan-Lam S-芳基化。 在改性的 Suzuki 和 Still 交叉偶联反应下，与铜催化的区域选择性交叉偶联反应。 存在碳酸二甲酯溶剂的情况下的无金属联芳基偶联反应。 不存在碱的情况下与五价三芳基二乙酸锑的Suzuki 交叉偶联反应。 它还可用于制备： 喜巴辛类似物，作为凝血酶受体拮抗剂和潜在的抗血小板药物。 三磺化杯芳烃上限磺胺嘧啶，以及具有三甲基赖氨酸表观遗传标记的络合物。 抗疟疾化合物，通过 Suzuki 交叉偶联反应制得。 脱氧尿苷衍生物 作为反应物，参与以下反应： 氧化羟基化 三氟甲基化 1,4-加成反应 合成以下抑制剂的前体，例如： Tpl2 激酶抑制剂 用于治疗疼痛的 P2X7 拮抗剂 4-Cyanophenylboronic acid can be used as a reactant in: Palladium-catalyzed Suzuki-Miyaura cross-coupling in water. Ruthenium catalyzed direct arylation of benzylic sp3 carbons of acyclic amines with arylboronates. Ligand-free copper-catalyzed coupling of nitro arenes with arylboronic acids. Ferric perchlorate-promoted reaction of fullerenes with various arylboronic acids to give fullerenyl boronic esters. Phosphine-free Suzuki-Miyaura cross-coupling. Palladacycles as effective catalysts for multicomponent reaction with allylpalladium-intermediates. Chan-Lam-type Cu-catalyzed S-arylation of thiols. Regioselective cross-coupling reactions under modfied Suzuki and Still cross-coupling reactions with copper catalysis. Metal-free biaryl coupling reaction in the presence of dimethyl carbonate as a solvent. Suzuki-type cross-coupling reaction with pentavalent triarylantimony diacetates in the absence of a base. It can also be used to prepare: Himbacine analogs as thrombin receptor antagonists and potential antiplatelet agents. Trisulfonated calixarene upper-rim sulfonamido and their complexation with trimethyllysine epigenetic mark. Antimalarial compounds via Suzuki cross-coupling. Deoxyuridine derivatives. Reactant involved in: Oxidative hydroxylation Trifluoromethylation 1,4-Addition reactions Precursor in the synthesis of inhibitors such as: Tpl2 kinase inhibitors P2X7 antagonists used in the treatment of pain
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4-Cyanophenylboronic acid（contains varying amounts of anhydride）
Dangerous GoodsCAS number：126747-14-6 molecular formula：C7H6BNO2
overview
compound introduction
Specs
| Chinese alias | 对氰基苯硼酸 | ||
| English alias | 4-cyanobenzene boronic acid | B-(4-cyanophenyl)-boronic acid | 4-cyanophenyl-boronic acid | AKOS004116072 | (4-cyanophenyl) boronic acid | BCP12932 | J-515232 | BBL101374 | 4-Cyanobenzeneboronic Acid | para-cyanophenylboronic acid | SCHEMBL6016 | Z9153806 | ||
| CAS number | 126747-14-6 | molecular formula | C7H6BNO2 |
| molecular weight | 146.94 g/mol | Exact mass | ≥97% |
| PSA | 64.300 Ų | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS06 , GHS07
Signal word：
Danger
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H301: 吞咽会中毒 H311: 皮肤接触有毒 H331: 吸入会中毒 H302: 吞食有害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水
WGK Germany：
3
Personal protective equipment：
Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter
UN Number：
2811
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
126747-14-6 | 4-Cyanophenylboronic acid.pdf
