CAS number：127373-66-4 molecular formula：C20H22N2O7S
Sivelestat (EI546) 是竞争性的人类中性粒细胞弹性蛋白酶的抑制剂，其 IC50 值为 44 nM， Ki 值为 200 nM。Sivelestat (EI546) 有潜力用于 COVID-19 的急性肺损伤/急性呼吸窘迫综合征或弥散性血管内凝血的研究。 Product description Sivelestat (EI546) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19
| Chinese alias | - | ||
| English alias | dl-N-Acetylhomocysteinethiolactone | ONO5046;LY544349;EI546 | SIVELESTAT [INN] | SIVELESTAT [MART.] | 2,2-Dimethyl-propionic acid 4-[2-(carboxymethyl-carbamoyl)-phenylsulfamoyl]-phenyl ester | P,.ALPHA.,.ALPHA.-TRIMETHYLBENZYL ALCOHOL [FHFI] | J-005486 | | ||
| CAS number | 127373-66-4 | molecular formula | C20H22N2O7S |
| molecular weight | 434.46 g/mol | Exact mass | - |
| PSA | 147.000 Ų | logp | 3 |
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