compound introduction
TNP 470是烟曲霉素的类似物，在体外显示有效的抗血管生成活性。已显示出抑制MetAP-2（甲硫氨酸氨基肽酶II型）的作用。 TNP 470 is an analog of Fumagillin that displays potent antiangiogenic activity in vitro. Shown to inhibit MetAP-2 (methionine aminopeptidase type II ).
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TNP 470
Dangerous GoodsCAS number：129298-91-5 molecular formula：C19H28CINO6
overview
Specs
| Chinese alias | - | ||
| English alias | AGM-1470 | CCRIS 8049 | (CHLOROACETYL)CARBAMIC ACID (3R,4S,5S,5R)-5-METHOXY-4-[(2R,3R)-2-METHYL-3-(3-METHYL-2-BUTENYL)OXIRANYL]-1-OXASPIRO[2.5]OCT-6-YL ESTER | Carbamic acid, (chloroacetyl)-, 5-methoxy-4-(2-methyl-3-(3-methyl-2-butenyl)oxiranyl)-1-oxaspir | ||
| CAS number | 129298-91-5 | molecular formula | C19H28CINO6 |
| molecular weight | 401.88 g/mol | Exact mass | ≥97% |
| PSA | 89.700 Ų | logp | 2.500 |
numbering system
No numbering system information yet
physicochemical properties
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移
WGK Germany：
2
Production methods and uses
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upstream information
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downstream information
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MSDS
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