Latanoprost是前列腺素F2α的类似物,是前列腺素类选择性FP受体的激动剂。Latanoprost增加葡萄膜巩膜外流,因而减少眼压。(Latanoprost is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect. Latanoprost increases uveoscleral outflow and thereby reduces intraocular pressure.) 应用: 拉坦前列素已被用于: 制备包含姜黄素纳米颗粒(CUR-NP)的热敏水凝胶,以确定其在氧化应激下对人小梁网(TM)细胞的治疗作用。 作为酯类前药用于研究其对小鼠鼠眼表面的作用 制备热敏水凝胶用于研究其对控制高眼压症的作用。 Latanoprost is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect. Latanoprost increases uveoscleral outflow and thereby reduces intraocular pressure.
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Latanoprost
Dangerous GoodsCAS number:130209-82-4 molecular formula:C26H40O5
overview
compound introduction
Specs
| Chinese alias | 拉坦前列素 | 异丙基 (5Z,9α,11α,15R)-9,11,15-三羟基-17-苯基-18,19,20-三硝基苯-5-烯-1-酸酯 | 异丙基 ( Z )-7-[(1 R ,2 R ,3 R ,5 S )-3,5-二羟基-2-[(3 R )-3-羟基-5-苯戊基] 环戊基] 庚烯-5-酸酯 | 适利达 | 拉坦前列腺素 | ||
| English alias | AB00640005-06 | HY-B0577 | LATANOPROST [VANDF] | XA41 | XA-41 | (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptanoic acid 1-methylethyl ester | (Z)-isopropyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R)-3-hydroxy-5-phenyl | ||
| CAS number | 130209-82-4 | molecular formula | C26H40O5 |
| molecular weight | 432.59 g/mol | Exact mass | - |
| PSA | 87.000 Ų | logp | 4.3 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS06 , GHS08
Signal word:
Danger
Hazard Statement:
H301: 吞咽会中毒 H300: 吞咽致命 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures:
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P203: 使用前,获取、阅读并遵守所有安全说明。 P301+P316: 如果吞咽:立即寻求紧急医疗救助。 P318: 如果暴露或担心,请就医。
WGK Germany:
3
Personal protective equipment:
Eyeshields, Faceshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS:
MJ9669550
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
130209-82-4 | Latanoprost for system suitability.pdf





