Tolcapone是一种有效和选择性的可逆硝基酚类儿茶酚-O-甲基转移酶(COMT)抑制剂,Ki为30nM。An inhibitor of peripheral and central catechol-O-methyltransferase. Tolcapone is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with Ki of 30 nM. An inhibitor of peripheral and central catechol-O-methyltransferase.
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Tolcapone
Dangerous GoodsCAS number:134308-13-7 molecular formula:C14H11NO5
overview
compound introduction
Specs
| Chinese alias | 托卡朋 | ||
| English alias | NCGC00181767-02 | 5-[(4-METHYLPHENYL)CARBONYL]-3-NITROBENZENE-1,2-DIOL | C07949 | TOLCAPONE (USP MONOGRAPH) | N04BX01 | 5-(4-methylbenzoyl)-3-nitrobenzene-1,2-diol | CAS-134308-13-7 | SR-05000001444 | Tolcapone, >=98% (HPLC) | Tox21_112963 | DB00323 | MFC | ||
| CAS number | 134308-13-7 | molecular formula | C14H11NO5 |
| molecular weight | 273.24 g/mol | Exact mass | - |
| PSA | 103.000 Ų | logp | 3.3 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS09
Signal word:
Warning
Hazard Statement:
H400: 对水生生物有剧毒
Statement of Preventive Measures:
P273: 避免释放到环境中。 P501: 将内容物/容器处理到。。。 P391: 收集溢出物
RTECS:
PC4952500
Production methods and uses
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MSDS
Found 1 shareMSDS
134308-13-7 | TOLCAPONE, UNITED STATESPHARMACOPEIA (USP) REFERENCESTANDARD.pdf





