Rasagiline

Dangerous Goods

CAS number：136236-51-6 molecular formula：C12H13N

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Rasagiline是一种选择性的、不可逆的MAO-B炔丙胺抑制剂，对MAO-B和MAO-A的IC50分别为4.43 nM和412 nM。甲磺酸雷沙吉兰可被用于MAO B型介导的细胞信号转导研究。 Rasagiline mesylate has been used: • to test its neuroprotective effects in retinitis pigmentosa (RP) by apoptosis regulator, Bax/Bcl-2 modulation • as monoamine oxidase-B inhibitor in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced mouse model • as an anti-parkinsonian agent to test its rescue functionality in 6-hydroxydopamine-lesioned zebrafish larvae towards bradykinetic and dyskinetic-like behavior.

Specs

Chinese alias	雷沙吉兰 \| (R)-N-2-丙炔基-1-氢化茚胺甲磺酸盐甲磺酸酯, TVP-1012, 马来酸雷沙吉兰甲磺酸酯
English alias	rasagiline \| 136236-51-6 \| (R)-N-(2-Propynyl)-2,3-dihydroinden-1-amine \| Azilect \| (R)-N-2-Propynyl-1-indanamine \| (1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine \| (R)-2,3-dihydro-N-2-propynyl-1H-inden-1-amine \| 1-Indanamine, N-2-propynyl-, (R)- \| T
CAS number	136236-51-6	molecular formula	C12H13N
molecular weight	171.24 g/mol	Exact mass	-
PSA	12.000 Å²	logp	1.800

numbering system

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physicochemical properties

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Safety information

pictogram：

GHS07

Signal word：

Warning

Hazard Statement：

H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H302: 吞食有害

Statement of Preventive Measures：

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水