Abacavir是强力的核苷类似物,为逆转录酶抑制剂。Abacavir exhibits antiviral activity. It is associated with myocardial infarction and fatal hypersensitivity reaction (HSR).Abacavir sulfate has been used as a compound to validate the P19C5 gastrulation in mouse. It has also been used to induces chromosomal double-strand breaks (DSBs) and kills adult T cell leukemia (ATL) cells. Abacavir sulfate has been used in the cytotoxicity to test its tumour promoting activity U937 cells. Abacavir is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Abacavir exhibits antiviral activity. It is associated with myocardial infarction and fatal hypersensitivity reaction (HSR).
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Abacavir
Dangerous GoodsCAS number:136470-78-5 molecular formula:C14H18N6O
overview
compound introduction
Specs
| Chinese alias | 阿巴卡韦 | 阿巴卡维 | (1S,4R)-4-[2-氨基-6-(环丙氨基)-9H-嘌呤-9-基]-2-环戊烯-1-甲醇 | ||
| English alias | ((1s,4r)-4-(2-amino-6-(cyclopropylamino)-9h-purin-9-yl)cyclopent-2-enyl)methanol | Avacavir | Epitope ID:137341 | MFCD00903850 | AVACAVIR [VANDF] | MCGSCOLBFJQGHM-SCZZXKLOSA-N | A807079 | AB01566826_01 | WR2TIP26VS | NSC 742406 | SMR004701251 | (+/-)-cis- | ||
| CAS number | 136470-78-5 | molecular formula | C14H18N6O |
| molecular weight | 286.33 g/mol | Exact mass | - |
| PSA | 102.000 Ų | logp | 0.900 |
numbering system
No numbering system information yet
physicochemical properties
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Safety information
pictogram:
GHS08 , GHS07
Signal word:
Warning
Hazard Statement:
H319: 引起严重眼睛刺激 H341: 怀疑引起遗传缺陷 H351: 怀疑引起遗传缺陷 H302: 吞食有害 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures:
P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P281: 根据需要使用个人防护设备。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P203: 使用前,获取、阅读并遵守所有安全说明。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P31
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MSDS
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