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Abacavir

Dangerous Goods

CAS number:136470-78-5    molecular formula:C14H18N6O

overview

compound introduction

Abacavir是强力的核苷类似物,为逆转录酶抑制剂。Abacavir exhibits antiviral activity. It is associated with myocardial infarction and fatal hypersensitivity reaction (HSR).Abacavir sulfate has been used as a compound to validate the P19C5 gastrulation in mouse. It has also been used to induces chromosomal double-strand breaks (DSBs) and kills adult T cell leukemia (ATL) cells. Abacavir sulfate has been used in the cytotoxicity to test its tumour promoting activity U937 cells. Abacavir is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Abacavir exhibits antiviral activity. It is associated with myocardial infarction and fatal hypersensitivity reaction (HSR).

Specs

Chinese alias阿巴卡韦 | 阿巴卡维 | (1S,4R)-4-[2-氨基-6-(环丙氨基)-9H-嘌呤-9-基]-2-环戊烯-1-甲醇
English alias((1s,4r)-4-(2-amino-6-(cyclopropylamino)-9h-purin-9-yl)cyclopent-2-enyl)methanol | Avacavir | Epitope ID:137341 | MFCD00903850 | AVACAVIR [VANDF] | MCGSCOLBFJQGHM-SCZZXKLOSA-N | A807079 | AB01566826_01 | WR2TIP26VS | NSC 742406 | SMR004701251 | (+/-)-cis-
CAS number136470-78-5molecular formulaC14H18N6O
molecular weight286.33 g/molExact mass-
PSA102.000 Ųlogp0.900

numbering system

No numbering system information yet

physicochemical properties

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Safety information

pictogram:
GHS08 , GHS07
Signal word:
Warning
Hazard Statement:
H319: 引起严重眼睛刺激 H341: 怀疑引起遗传缺陷 H351: 怀疑引起遗传缺陷 H302: 吞食有害 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures:
P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P281: 根据需要使用个人防护设备。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P330: 漱口 P203: 使用前,获取、阅读并遵守所有安全说明。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P31

Production methods and uses

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Related

upstream information

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downstream information

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MSDS

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