Voriconazole (伏立康唑; UK-109496) 是第二代三唑类抗真菌化合物,可作用于严重的真菌感染。An antifungal CYP2C9 inhibitor Voriconazole is a new triazole derivative similar to fluconazole and itraconazole that acts by inhibiting fungal cytochrome P-450-dependent, 14-alpha-sterol demethylase-mediated synthesis of ergosterol. An antifungal CYP2C9 inhibitor
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Voriconazole
Dangerous GoodsCAS number:137234-62-9 molecular formula:C16H14F3N5O
overview
compound introduction
Specs
| Chinese alias | 伏立康唑 | 2R,3S-2-(2,4-二氟苯基)-3-(5-氟嘧啶-4-基)-1-(1H-1,2,4-三唑-1-基)丁-2-醇 | ||
| English alias | VORICONAZOLE [EMA EPAR] | Voriconazole, Pharmaceutical Secondary Standard: Certified Reference Material | AB00639948_08 | CHEBI:10023 | Tox21_500150 | V0116 | Voriconazol | BDBM50333117 | Delnav | HY-W337569 | ( inverted exclamation markA)-Voriconazole | | ||
| CAS number | 137234-62-9 | molecular formula | C16H14F3N5O |
| molecular weight | 349.31 g/mol | Exact mass | - |
| PSA | 76.700 Ų | logp | 1.5 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS06 , GHS08 , GHS09
Signal word:
Danger
Hazard Statement:
H301: 吞咽会中毒 H351: 怀疑引起遗传缺陷 H373: 通过长时间或反复暴露对器官造成损害 H412: 对水生生物有害并具有长期持续影响 H400: 对水生生物有剧毒 H360: 可能损害生育力或未出生的孩子 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures:
P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P391: 收集溢出物 P330: 漱口 P203: 使用前,获取、阅读并遵守所有安全说明。 P301+P316: 如果吞咽:立即寻求紧急医疗救助。 P318: 如果暴
WGK Germany:
3
RTECS:
UV9145000
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 1 shareMSDS
137234-62-9 | VORICONAZOLE, UNITED STATESPHARMACOPEIA (USP) REFERENCESTANDARD.pdf





