compound introduction
Pemetrexed是抗叶酸和抗代谢剂，对TS，DHFR和GARFT的Ki分别为1.3 nM，7.2 nM和65 nM。 Pemetrexed is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.
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Pemetrexed
Dangerous GoodsCAS number：137281-23-3 molecular formula：C20H21N5O6
overview
Specs
| Chinese alias | - | ||
| English alias | GTPL5443 | N-({4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]phenyl}carbonyl)-L-glutamic acid | Pemetrexed (TN) | (2S)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid | BP164240 | ||
| CAS number | 137281-23-3 | molecular formula | C20H21N5O6 |
| molecular weight | 427.41 g/mol | Exact mass | - |
| PSA | 187.000 Ų | logp | 0.200 |
numbering system
No numbering system information yet
physicochemical properties
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Safety information
pictogram：
GHS08 , GHS07
Signal word：
Danger
Hazard Statement：
H351: 怀疑引起遗传缺陷 H302: 吞食有害 H360: 可能损害生育力或未出生的孩子
Statement of Preventive Measures：
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P203: 使用前，获取、阅读并遵守所有安全说明。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P318: 如果暴露或担心，请就医。
RTECS：
LZ9950100
Production methods and uses
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MSDS
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