Valsartan是一种血管紧张素II受体拮抗剂,IC50在39.5到116 μM之间。使用缬沙坦治疗小鼠,以研究Ang II依赖性途径对醛固酮相关作用的影响。 Valsartan is an angiotensin II receptor antagonist with IC50 of ranging from 39.5 to 116 μM. Valsartan is an orally active specific angiotensin II receptor blocker used for the treatment of hypertension A nonpeptide angiotensin II AT1 receptor antagonist.
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Valsartan
Dangerous GoodsCAS number:137862-53-4 molecular formula:C24H29N5O3
overview
compound introduction
Specs
| Chinese alias | 缬沙坦 | N-(1-氧代戊基)-N-[[2'-(2H-四唑-5-基)[1,1'-联苯]-4-基]甲基]-L-缬氨酸 | ||
| English alias | HSDB 7519 | Valsartan [USAN:USP:INN:BAN] | 80M03YXJ7I | Tareg | VALSARTAN (USP-RS) | MLS001424088 | VALSARTAN [INN] | ENTRESTO COMPONENT VALSARTAN | Spectrum_001796 | Miten | VALSARTAN [MART.] | VALSARTAN [VANDF] | VALSARTAN [EMA EPAR] | VALSARTAN [HSDB] | ||
| CAS number | 137862-53-4 | molecular formula | C24H29N5O3 |
| molecular weight | 435.52 g/mol | Exact mass | - |
| PSA | 112.000 Ų | logp | 4.4 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS08
Signal word:
Warning
Hazard Statement:
H412: 对水生生物有害并具有长期持续影响 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures:
P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P203: 使用前,获取、阅读并遵守所有安全说明。 P318: 如果暴露或担心,请就医。
WGK Germany:
3
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MSDS
Found 1 shareMSDS
137862-53-4 | Valsartan (350 mg).pdf





