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Brinzolamide

Dangerous Goods

CAS number：138890-62-7    molecular formula：C12H21N3O5S3

overview
Specs
numbering system
physicochemical properties
Safety information
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overview

compound introduction

Brinzolamide (AL-4862) 是一种选择性的碳酸酐酶II（carbonic anhydrase II）抑制剂，其 IC50 值为 3.2 nM。Brinzolamide 可以通过抑制睫状体 CA-II，降低房水分泌，从而降低眼压 (IOP)。可用于青光眼疾病的研究。 Brinzolamide (AL-4862) is a selective carbonic anhydrase II inhibitor with anIC50 value of 3.2 nM. Brinzolamide hydrochloride reduces intraocular pressure (IOP) by inhibiting ciliary CA-II and decreasing atrial fluid secretion. Brinzolamide can be used in glaucoma disease research

Specs

Chinese alias-
English aliasAzopt | Brinzolamide | AL-4862 | (4R)-4-(ethylamino)-2-(3-methoxypropy1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide
CAS number138890-62-7molecular formulaC12H21N3O5S3
molecular weight383.51 g/molExact mass-
PSA164.000 Ųlogp-0.300

numbering system

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physicochemical properties

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Safety information

pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害 H312: 皮肤接触有害 H332: 吸入有害 H302+H332: 吞咽或吸入有害。
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用
WGK Germany：
3
RTECS：
XJ9095055

Production methods and uses

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MSDS

Found 1 shareMSDS
138890-62-7 | Brinzolamide, United States Pharmacopeia(USP) Reference Standard.pdf