Levosimendan 是一种钙增敏剂,通过与cardiac troponin C (cTnC)结合而发挥作用,这种作用具有钙依赖性。A Ca2+ sensitizer that increases contractile force of the myocardium. Levosimendan is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC), provides treatment for heart failure. A Ca2+ sensitizer that increases contractile force of the myocardium.
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Levosimendan
Dangerous GoodsCAS number:141505-33-1 molecular formula:C14H12N6O
overview
compound introduction
Specs
| Chinese alias | 左西孟旦 | ||
| English alias | OR1259 | HMS3884N17 | levosimendanum | Tox21_112191_1 | SR-01000931342-2 | DTXSID9046445 | Levosimendan [USAN:INN] | Simsndan;OR-1259 | ({4-[(4R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl]phenyl}hydrazono)propanedintrile | (R)-((4-(1,4,5,6-Tetrahydr | ||
| CAS number | 141505-33-1 | molecular formula | C14H12N6O |
| molecular weight | 280.28 g/mol | Exact mass | ≥98% |
| PSA | 113.000 Ų | logp | 2.3 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H302: 吞食有害 H312: 皮肤接触有害 H332: 吸入有害
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。 P362+P364: 脱掉沾污的衣服,清洗后方可重新使用
WGK Germany:
3
RTECS:
TY1570210
Production methods and uses
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Related
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MSDS
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