Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Target: NRTIs; HBV Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Adefovir Dipivoxil is used for treatment of hepatitis B and herpes simplex virus infection [1-3]. Adefovir Dipivoxil is approved for the treatment of chronic hepatitis B in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (primarily ALT) or histologically active disease. Adefovir Dipivoxil is a failed treatment for HIV[3, 4]. Adefovir dipivoxil 是一种腺苷类似物，是核苷逆转录酶 (nucleoside reverse transcriptase) 抑制剂 Adefovir 的口服前体。Adefovir dipivoxil 对 Lamivudine 耐药株和野生型菌株均有抑制作用。Adefovir dipivoxil 具有抗正痘病毒活性。 Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Target: NRTIs; HBV Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Adefovir Dipivoxil is used for treatment of hepatitis B and herpes simplex virus infection [1-3]. Adefovir Dipivoxil is approved for the treatment of chronic hepatitis B in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (primarily ALT) or histologically active disease. Adefovir Dipivoxil is a failed treatment for HIV[3, 4]. Catalyst employed in the Sharpless Asymmetric Dihyroxylation of ( E , E )- or ( E , Z )-1,3-dienoates. 1 Also used in the preparation of ?-hydroxy-γ-lactones from ?,γ-unsaturated esters. 2 Product Introduction: Adefovir dipivoxil, an adenosine analogue, is an oral proagent of the nucleoside reverse transcriptase inhibitor Adefovir. Adefovir dipivoxil inhibits both the wild type and HBV Lamivudine-resistant strains. Adefovir dipivoxil shows anti-orthopoxvirus activity.
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Adefovir Dipivoxil
Dangerous GoodsCAS number：142340-99-6 molecular formula：C20H32N5O8P
overview
compound introduction
Specs
| Chinese alias | 阿德伏韦酯 | 阿德幅韦二脂 | 9-[2-[双(新戊酰氧基甲氧基)磷酰甲氧基]乙基]腺嘌呤 | ||
| English alias | 9-[2-[Bis(pivaloyloxymethoxy)phosphorylmethoxy]ethyl]adenine | 9-(2[bis(Pivaloyloxymethoxy)phosphorylmethoxy]ethyl)adenine | ||
| CAS number | 142340-99-6 | molecular formula | C20H32N5O8P |
| molecular weight | 501.47 g/mol | Exact mass | ≥99% |
| PSA | 167.000 Ų | logp | 1.8 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H302: 吞食有害 H312: 皮肤接触有害 H332: 吸入有害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用
WGK Germany：
3
RTECS：
UA2459362
Production methods and uses
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Related
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downstream information
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MSDS
Found 1 shareMSDS
14 2340-99 - 6 | Adefovir dipivoxil | Adefovir dipivoxil
