Elacridar(GF120918; GW0918)是P-糖蛋白抑制剂,在体内外实验中常作为工具化合物。 Elacridar (GF120918; GW0918) is a P-glycoprotein inhibitor and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. A prototypical BCRP (ABCG2) inhibitor.
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Elacridar
Dangerous GoodsCAS number:143664-11-3 molecular formula:C34H33N3O5
overview
compound introduction
Specs
| Chinese alias | GF 120918 | 依克立达 | N-[4-[2-(3,4-二氢-6,7-二甲氧基-2(1H)-异喹啉基)乙基]苯基]-9,10-二氢-5-甲氧基-9-氧代-4-吖啶甲酰胺 | N-[4-[2-(3,4-二氢-6,7-二甲氧基-2 (1H)-异喹啉基)乙基] 苯基]-9,10-二氢-5-甲氧基-9-氧代-4-吖啶甲酰胺 | ||
| English alias | Elacridar | 143664-11-3 | GF120918 | Elacridar [INN] | GF-120918 | GG918 | N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-5-methoxy-9-oxo-10H-acridine-4-carboxamide | Elacridar (GF120918) | GF 120918 | CHEMBL396298 | N-(4-(2-(6,7-dim | ||
| CAS number | 143664-11-3 | molecular formula | C34H33N3O5 |
| molecular weight | 563.64 g/mol | Exact mass | 10mM in DMSO |
| PSA | 89.100 Ų | logp | 5.600 |
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Safety information
WGK Germany:
3
RTECS:
AR7621300
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