CAS number：144060-53-7 molecular formula：C16H16N2O3S
Febuxostat (非布司他; TEI 6720;TMX 67 ) 是选择性黄嘌呤氧化酶（XO）抑制剂，Ki为0.6 nM。An inhibitor xanthine oxidase and xanthine dehydrogenase Product Description： Febuxostat(TEI 6720;TMX 67 ) is selective xanthine oxidase inhibitor with Ki of 0.6 nM.An inhibitor xanthine oxidase and xanthine dehydrogenase. Febuxostat is a potent, non-purine compound, which inhibits the expression of cytokines/chemokines. It has also been reported to inhibit LPS-induced TNF-α, VCAM-1, MMP9 and MCP-1 expression.
| Chinese alias | 2-(3-氰基-4-异丁氧基苯基)-4-甲基噻唑-5-甲酸 | 2-(3-氰基-4-异丁氧基苯基)-4-甲基-1,3-噻唑-5-羧酸 | ||
| English alias | BC164443 | C16H16N2O3S | FEBUXOSTAT (MART.) | Febuxostat [USAN:INN:BAN] | HMS3655C03 | AC-425 | Q417296 | CCG-213303 | DTXSID8048650 | 2-(3-Cyano-4-(2-methylpropoxy)phenyl)-4-methylthiazole-5-carboxylic acid | Febuxostat | FEBUXOSTAT [VANDF] | 2-(3-Cyano- | ||
| CAS number | 144060-53-7 | molecular formula | C16H16N2O3S |
| molecular weight | 316.38 g/mol | Exact mass | - |
| PSA | 111.000 Ų | logp | 3.9 |
No numbering system information yet
No physical and chemical property information yet
No production method and use information yet
No upstream information yet
No downstream information yet
