Ivabradine HCl是一种新型If抑制剂,IC50为2.9 μM,特定有效作用于窦房结心脏起搏器活性,是一种纯粹的心跳速率降低剂。A selective bradycardic agent. Ivabradine HCl, a new If inhibitor with IC 50 of 2.9 μM which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent. A selective bradycardic agent.
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Ivabradine HCl
Dangerous GoodsCAS number:148849-67-6 molecular formula:C27H36N2O5 · HCl
overview
compound introduction
Specs
| Chinese alias | 盐酸伊伐布雷定 | ||
| English alias | 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one hydrochloride | Ivabradine HCl | IVABRADINE HYDROCHLORIDE [MI] | 2H-3-Benzazepin-2-one, 3-(3-(((3,4-dimethoxy | ||
| CAS number | 148849-67-6 | molecular formula | C27H36N2O5 · HCl |
| molecular weight | 505.05 g/mol | Exact mass | ≥98% |
| PSA | 60.500 Ų | logp | - |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS08 , GHS09 , GHS07
Signal word:
Danger
Hazard Statement:
H373: 通过长时间或反复暴露对器官造成损害 H302: 吞食有害 H400: 对水生生物有剧毒 H360: 可能损害生育力或未出生的孩子
Statement of Preventive Measures:
P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P391: 收集溢出物 P330: 漱口 P203: 使用前,获取、阅读并遵守所有安全说明。 P301+P317: 如果被吞咽:请寻求医疗帮助。 P318: 如果暴露或担心,请就医。 P319: 如果你感到不适,请寻求
WGK Germany:
3
Production methods and uses
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upstream information
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MSDS
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