β-Glycerophosphate disodium salt hydrate（BGP）

β-甘油磷酸盐是激酶反应缓冲液中丝氨酸-苏氨酸磷酸酶的一种经典抑制剂。BGP通常与其他磷酸酶/蛋白酶抑制剂组合，以实现广谱抑制。它可用作有机磷酸盐供体，并且已用于使间充质干细胞分化为成骨细胞型细胞的培养基。BGP也用于缓冲乳酸菌的M17培养基，以进行重组蛋白表达。对嵌入天然胶原/壳聚糖凝胶（用于组织工程）中的骨髓衍生干细胞进行诱导分化。应用： 甘油磷酸二钠盐水合物又称BGP，是一种用途广泛的化合物，应用于各种研究领域，包括细胞生物学、生化研究和代谢组学。BGP作为一种内源性代谢物和丝氨酸-苏氨酸磷酸酶抑制剂，被广泛应用于壳聚糖水凝胶配方，以投入给药研究。它是细胞生长和重组蛋白生产的磷酸盐来源，通过减少高pH水平下的沉淀，在培养基配方中具有优势。此外，BGP还可应用于微弧氧化电解质溶液，有助于创建光催化涂层。在细胞生物学中，β-甘油磷酸二钠盐作为磷酸基供体在基质矿化研究中起关键作用，可加速血管平滑肌细胞的钙化。当输送至成骨细胞，它还可促进骨基质矿化，提供磷酸盐离子的重要来源。在生物化学研究领域，BGP作为激酶反应缓冲液中的经典丝氨酸-苏氨酸磷酸酶抑制剂，具有广谱抑制作用。它可用作有机磷酸盐供体，在使间充质干细胞分化为成骨细胞型细胞的培养基中尤其有用。另外，在乳球菌培养物的重组蛋白表达体系中，BGP可用作M17培养基的缓冲组分。BGP的综合应用横跨多个研究领域，使其成为细胞生物学、生化研究和代谢组学研究的重要组分。 特点和优势： 用途广泛，适应各种实验室和研究应用； 适用于细胞培养和植物细胞培养； 经过测试，确认低水平的重金属污染，确保各种应用的适用性； 用于细胞生物学和生物化学研究的BioUltra级应用。 Glycerophosphoric acid disodium salt hydrate, also known as BGP, is a versatile compound with applications across various research domains, including cell biology, biochemical research, and metabolomics. Recognized as an endogenous metabolite and a serine-threonine phosphatase inhibitor, BGP is extensively utilized in chitosan hydrogel formulations for drug delivery research. It serves as a phosphate source for cell growth and recombinant protein production, offering advantages in media formulations by reducing precipitation at higher pH levels. Additionally, BGP finds applications in micro-arc oxidation electrolyte solutions, contributing to the creation of photocatalytic coatings. In cell biology, β-Glycerophosphate disodium salt plays a pivotal role as a phosphate group donor in matrix mineralization studies and accelerates calcification in vascular smooth muscle cells. It also promotes bone matrix mineralization when delivered to osteoblasts, providing a crucial source of phosphate ions. In the realm of biochemical research, BGP functions as a classical serine-threonine phosphatase inhibitor in kinase reaction buffers, offering broad-spectrum inhibition. Its role as an organic phosphate donor is particularly valuable in culture media for mesenchymal stem cell differentiation to osteoblast-type cells. Moreover, BGP is utilized to buffer M17 media for Lactococcus culture in recombinant protein expression. The comprehensive utility of BGP spans multiple areas of research, making it an essential component in studies encompassing cell biology, biochemical research, and metabolomics. Application: β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It functions as an organic phosphate donor and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells. BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression. Initiates differentiation of bone-marrow-derived stem cells embedded in a natural collagen/chitosan gel designed for tissue engineering.

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