Plerixafor 8HCl (AMD3100 8HCl)是Plerixafor的盐酸盐,是CXCR4趋化因子受体拮抗剂,作用于CXCR4和CXCL12调节的趋化性, IC50分别为44 nM和5.7 nM。 Plerixafor 8HCl (AMD3100 8HCl) is the hydrochloride of Plerixafor, a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively. A specific CXCR4 antagonist.
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Plerixafor 8HCl (AMD3100 8HCl)
CAS number:155148-31-5 molecular formula:C28H54N8·8HCl
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compound introduction
Specs
| Chinese alias | 普乐沙福八盐酸盐 | 1,4-双[(1,4,8,11-四氮杂环十四烷-1-基)甲基]苯八盐酸盐 | 1,1'-[1,4-亚苯基双(亚甲基)]双-1,4,8,11-四氮杂环十四烷八盐酸盐 | 普乐沙福 8HCl(AMD3100 8HCl) | ||
| English alias | 155148-31-5 (HCl) | Plerixafor hydrochloride | AMD3100 octahydrochloride hydrate | DTXSID20935148 | 1,1'-[1,4-Phenylenebis-(methylene)]-bis-(1,4,8,11-tetraazacyclotetradecane) octahydrochloride | Sid 791 | PLERIXAFOR OCTAHYDROCHLORIDE [WHO-DD] | AMD 3100 | ||
| CAS number | 155148-31-5 | molecular formula | C28H54N8·8HCl |
| molecular weight | 794.47 g/mol | Exact mass | 10mM in Water |
| PSA | 78.700 Ų | logp | - |
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