Ritonavir是一种HIV蛋白酶抑制剂,用于治疗HIV感染和AIDS。 产品介绍: Ritonavir (ABT 538) 是用于研究 HIV 感染和 AIDS 的 HIV 蛋白酶的抑制剂。Ritonavir 也是 SARS-CoV 3CLpro 的抑制剂,IC50 为 1.61 μM。 Ritonavir is an antiretroviral (HIV) drug which inhibits a particular liver enzyme that normally metabolizes protease inhibitors, cytochrome P450-3A4 (CYP3A4). Application: Ritonavir has been used: as a human immunodeficiency virus (HIV) protease inhibitor to study its effects on placental endocrine function as an HIV protease inhibitor to study its effects on reduction of tetrazolium dye in human embryonic kidney cells as an organic anion transporting polypeptide (OATP) inhibitor to study its effect on hepatic uptake of bergapten and imperatorin
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Ritonavir
Dangerous GoodsCAS number:155213-67-5 molecular formula:C37H48N6O5S2
overview
compound introduction
Specs
| Chinese alias | 利托那韦 | N-[(2S,3S,5S)-3-羟基-5-[[(2S)-3-甲基-2-[[甲基-[(2-异丙基-1,3-噻唑-4-基)甲基]氨基甲酰]氨基]丁酰]氨基]-1,6-二苯基-己-2-基]氨基甲酸 5-噻唑基甲基酯 | ||
| English alias | 2,4,7,12-Tetraazatridecan-13-oic acid, 10-hydroxy-2-methyl-5-(1-methylethyl)-1-[2-(1-methylethyl)-4-thiazolyl]-3,6-dioxo-8,11-bis(phenylmethyl)-, 5-thiazolylmethyl ester, [5S-(5R*,8R*,10R*,11R*)]- | 2,7,10,12-Tetraazatridecanoic acid, 4-hydroxy-12-methyl- | ||
| CAS number | 155213-67-5 | molecular formula | C37H48N6O5S2 |
| molecular weight | 720.94 g/mol | Exact mass | - |
| PSA | 202.000 Ų | logp | 6 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram:
GHS08 , GHS07
Signal word:
Warning
Hazard Statement:
H319: 引起严重眼睛刺激 H351: 怀疑引起遗传缺陷 H302: 吞食有害 H312: 皮肤接触有害 H332: 吸入有害 H302+H312+H332: 吞咽,皮肤接触或吸入有害。 H361: 怀疑破坏生育力或未出生的孩子
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270: 使用本产品时,请勿进食、饮水
WGK Germany:
3
RTECS:
XA5310000
Production methods and uses
No production method and use information yet
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upstream information
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downstream information
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MSDS
Found 1 shareMSDS
155213-67-5 | Ritonavir.pdf





