compound introduction
Indisulam (E 7070) 是一种碳酸酐酶抑制剂，具有抗癌活性。Indisulam (E 7070) 是细胞周期 G1 期的靶向化合物。Indisulam (E 7070) 通过抑制 CDK2 和周期蛋白 E 的激活，引起 G1/S 转化被阻滞。Indisulam (E 7070) 通过募集 DCAF15 诱导 RBM39 降解来靶向剪接。
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Indisulam
Dangerous GoodsCAS number：165668-41-7 molecular formula：C14H12ClN3O4S2
overview
Specs
| Chinese alias | - | ||
| English alias | A2113 | D04522 | WJ98J3NM90 | Formaldehyde-2,4-dinitrophenylhydrazone 100 microg/mL in Acetonitrile | BDBM10890 | Indisulam [USAN:INN:BAN] | 1,4-Benzenedisulfonamide, N1-(3-chloro-1H-indol-7-yl)- | UNII-WJ98J3NM90 | E7070 | E-7070 | N~1~-(3-chloro-1H-indo | ||
| CAS number | 165668-41-7 | molecular formula | C14H12ClN3O4S2 |
| molecular weight | 385.85 g/mol | Exact mass | - |
| PSA | 139.000 Ų | logp | 1.800 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激
Statement of Preventive Measures：
P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
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