CAS number：165800-06-6 molecular formula：C5H10N2O7P2·H2O
Zoledronic acid(CGP 42446; ZOL 446)一水合物是PKC活化剂，能诱导多发性骨髓瘤细胞系凋亡和抑制hFOB细胞增殖。A highly potent bisphosphonate and activator of PKC. Zoledronic acid monohydrate(CGP 42446; ZOL 446) is an activator of protein kinase C with apoptotic effects on multiple myeloma cell lines. It inhibited proliferation of human foetal osteoblastic cell line (hFOB) with an IC50 of 40 uM. A highly potent bisphosphonate and activator of PKC.
| Chinese alias | 唑来膦酸 一水合物 | 1-羟基-2-(1-咪唑基)乙烷-1,1-二磷酸 一水合物 | P,P′-[1-羟基-2-（1H-咪唑-1-基）亚乙基]双膦酸 一水合物 | [1-羟基-2-（1H-咪唑-1-基）乙烷-1,1-二基]双（膦酸） 一水合物 | ||
| English alias | CGP-42446A | ZOLEDRONIC ACID [USP MONOGRAPH] | Tox21_112486 | Zoledronate hydrate | Zoledronate monohydrate;CGP 42446 monohydrate;CGP42446A monohydrate;ZOL 446 monohydrate | Zoledronic acid monohydrate, >=98% (HPLC) | Zoledronic Acid Teva Pharma | CCG-222 | ||
| CAS number | 165800-06-6 | molecular formula | C5H10N2O7P2·H2O |
| molecular weight | 290.11 g/mol | Exact mass | - |
| PSA | 154.000 Ų | logp | - |
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