Avasimibe抑制ACAT,IC50为3.3 μM,也抑制人P450同工酶CYP2C9, CYP1A2和CYP2C19,IC50分别为2.9 μM, 13.9 μM和26.5 μMA cholesterol reducing compound that also inhibits CYP Avasimibe inhibits ACAT with IC50 of 3.3 μM, also inhibits human P450 isoenzymes CYP2C9, CYP1A2 and CYP2C19 with IC50 of 2.9 μM, 13.9 μM and 26.5 μM, respectively. A cholesterol reducing compound that also inhibits CYP
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Avasimibe
Dangerous GoodsCAS number:166518-60-1 molecular formula:C29H43NO4S
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compound introduction
Specs
| Chinese alias | - | ||
| English alias | (6X,10S)-6-(6,10-Dihydroxyundecyl)-.beta.-resorcylic acid .mu.-lactone | AVASIMIBE [WHO-DD] | AVASIMIBE [INN] | CI1011 | CI-1011 | SB19572 | [2,6-di(propan-2-yl)phenyl] N-[2-[2,4,6-tri(propan-2-yl)phenyl]acetyl]sulamate | Avasimibe [USAN] | Avasimibe,CI-1 | ||
| CAS number | 166518-60-1 | molecular formula | C29H43NO4S |
| molecular weight | 501.72 g/mol | Exact mass | ≥98% |
| PSA | 80.900 Ų | logp | 8.2 |
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