Posaconazole

Dangerous Goods

CAS number：171228-49-2 molecular formula：C37H42F2N8O4

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Posaconazole 是甾醇C14ɑ去甲基化酶抑制剂，IC50为0.25 nM。A triazole anti-fungal Product Application： Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.Posaconazole may have been used as reference standard in HPLC analysis for quantification of posaconazole from human plasma.

Specs

Chinese alias	泊沙康唑
English alias	HSDB 7421 \| 2,5-anhydro-1,3,4-trideoxy-2-(2,4-difluorophenyl)-4-({4-[4-(4-{1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl}phenyl)piperazin-1-yl]phenoxy}methyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol \| BP164281 \| P2477 \| AB
CAS number	171228-49-2	molecular formula	C37H42F2N8O4
molecular weight	700.78 g/mol	Exact mass	-
PSA	112.000 Å²	logp	4.6

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS08 , GHS09 , GHS07

Signal word：

Danger

Hazard Statement：

H319: 引起严重眼睛刺激 H351: 怀疑引起遗传缺陷 H400: 对水生生物有剧毒 H410: 对水生生物有剧毒并具有长期持续影响 H372: 通过长时间或反复暴露对器官造成损害 H361: 怀疑破坏生育力或未出生的孩子

Statement of Preventive Measures：

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P391: 收集溢出物 P203: 使用前，获取、阅读并遵守所有安全说明。 P264+P265: 处