CAS number：188968-51-6 molecular formula：C27H40N8O7
Cilengitide是一种有效的integrin（整合素）抑制剂，作用于αvβ3受体和αvβ5受体，IC50分别为4.1 nM和79 nM，比作用于gpIIbIIIa选择性高10倍左右。 Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM, respectively; ~10-fold selectivity against gpIIbIIIa.
| Chinese alias | NSC 707544 | 西仑吉肽 | ||
| English alias | EMD 121974 | EMD-121974 | EMD121974 | Cyclo(L-arginylglycyl-L-aspartyl-D-phenylalanyl-N-methyl-L-valyl) | ||
| CAS number | 188968-51-6 | molecular formula | C27H40N8O7 |
| molecular weight | 588.66 g/mol | Exact mass | - |
| PSA | 238.000 Ų | logp | -1 |
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