CAS number：192185-72-1 molecular formula：C27H22Cl2N4O
Pre-clinical studies show that tipifarnib has antiproliferative effects on pancreatic cancer cell lines at clinically relevant concentrations (concentration that inhibits 50% growth [IC50] from 9.5 to 500 nmol/L). It also exhibits marked growth retardation and antiangiogenic effects in a pancreatic cancer xenograft model.
| Chinese alias | - | ||
| English alias | (+)-(r)-6-[amino(4-chlorophenyl)(1-methyl-1h-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1h)-quinolinone | 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one | DS-14724 | HMS3748E21 | Q-102 | ||
| CAS number | 192185-72-1 | molecular formula | C27H22Cl2N4O |
| molecular weight | 489.4 g/mol | Exact mass | - |
| PSA | 64.200 Ų | logp | 4.1 |
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