Deferasirox(Exjade) is a rationally-designed oral iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic anemias. The half-life of deferasirox is between 8 and 16 hours allowing once a day dosingA tridentate chelator that binds iron with high affinity Deferasirox(Exjade) is a rationally-designed oral iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic anemias. The half-life of deferasirox is between 8 and 16 hours allowing once a day dosing A tridentate chelator that binds iron with high affinity
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Deferasirox
Dangerous GoodsCAS number：201530-41-8 molecular formula：C21H15N3O4
overview
compound introduction
Specs
| Chinese alias | 地拉罗司 | ||
| English alias | Exjade | ICL 670 | 4-(3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)benzoic acid | Deferasirox 100 microg/mL in Acetonitrile | Deferasorox | Deferasirox (Exjade) | Q2838752 | Deferasirox Oral Granules | FT-0601564 | BOFQWVMAQOTZIW-UHFFFAOYSA-N | DEFERASI | ||
| CAS number | 201530-41-8 | molecular formula | C21H15N3O4 |
| molecular weight | 373.36 g/mol | Exact mass | ≥99% |
| PSA | 108.000 Ų | logp | 3.8 |
numbering system
No numbering system information yet
physicochemical properties
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Safety information
pictogram：
GHS08 , GHS09 , GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H413: 可能对水生生物造成长期的有害影响 H302: 吞食有害 H312: 皮肤接触有害 H332: 吸入有害 H410: 对水生生物有剧毒并具有长期持续影响 H361: 怀疑破坏生育力或未出生的孩子 H312+H332: 皮肤接触或吸入有害。
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270
Production methods and uses
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MSDS
Found 1 shareMSDS
201530-41-8 | Deferasirox CRS.pdf
