Dabuzalgron (Ro 115-1240) 是一种选择性的 α-1A 肾上腺素能受体激动剂,动物模型中,用于缓解尿失禁。Dabuzalgron 可通过维持线粒体功能来预防由阿霉素引起的心脏毒性。 Dabuzalgron (Ro 115-1240) is a selective α-1A adrenergic receptor agonist for the treatment of urinary incontinence. Dabuzalgron protects against Doxorubicin-induced cardiotoxicity by preserving mitochondrial function.
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dabuzalgron
CAS number:219311-44-1 molecular formula:C12H16ClN3O3S
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| Chinese alias | 达布扎琼 | 达布扎隆 | ||
| English alias | 219311-44-1 (free base) | A911600 | N-(6-Chloro-3-((4,5-dihydro-1H-imidazol-2-yl)methoxy)-2-methylphenyl)methanesulfonamide | Dabuzalgron | HY-117071 | Dabuzalgron [INN] | CHEBI:142452 | GTPL3469 | LGX4GZ74WO | EX-A4502 | METHANESULFONAMIDE, N-(6-CHLORO-3 | ||
| CAS number | 219311-44-1 | molecular formula | C12H16ClN3O3S |
| molecular weight | 317.79 g/mol | Exact mass | - |
| PSA | 88.200 Ų | logp | 0.9 |
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