CAS number：220127-57-1 molecular formula：C29H31N7O.CH4SO3
Imatinib Mesylate (STI571)是Imatinib的甲磺酸盐，具有较好的口服生物利用度，是一种多靶点的抑制剂，同时作用于v-Abl， c-Kit和PDGFR，IC50分别为0.6 μM， 0.1 μM 和0.1 μM。A c-Abl, PDGFR, and c-kit inhibitor Imatinib Mesylate (STI571) is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively. A c-Abl, PDGFR, and c-kit inhibitor
| Chinese alias | 甲磺酸伊马替尼 | ||
| English alias | 4-[(4-methylpiperazin-1-yl)methyl]-N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}benzamide methanesulfonate | HB1943 | HMS2233D16 | IMATINIB MESILATE [MART.] | IMATINIB MESYLATE [HSDB] | Imatinib mesylate400 mg | J-523068 | Methanesulfonate, I | ||
| CAS number | 220127-57-1 | molecular formula | C29H31N7O.CH4SO3 |
| molecular weight | 589.71 g/mol | Exact mass | ≥99% |
| PSA | 149.000 Ų | logp | - |
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