compound introduction
Tosedostat (CHR-2797) 是一种氨基肽酶 (aminopeptidase) 抑制剂。CHR-2797 对多种肿瘤细胞系均具有抗增殖作用。作用于LAP， PuSA和Aminopeptidase N时，IC50分别为100 nM， 150 nM 和220 nM，不能有效抑制PILSAP， MetAP-2， LTA4水解酶，和MetAP-2。
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Tosedostat (CHR2797)
CAS number：238750-77-1 molecular formula：C21H30N2O6
overview
Specs
| Chinese alias | 托舍多特 | ||
| English alias | CHR-2797(Tosedostat) | Tosedostat | BCP9000524 | AC-375 | BENZENEACETIC ACID, .ALPHA.-(((2R)-2-((1S)-1-HYDROXY-2-(HYDROXYAMINO)-2-OXOETHYL)-4- METHYL-1-OXOPENTY)LAMINO)-, CYCLOPENTYL ESTER, (.ALPHA.S)- | Tosedostat [USAN:INN] | (5S,8S)-8-({(1R)-1-[3,5-bis | ||
| CAS number | 238750-77-1 | molecular formula | C21H30N2O6 |
| molecular weight | 406.47 g/mol | Exact mass | ≥95% |
| PSA | 125.000 Ų | logp | 2.3 |
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