Vildagliptin is a dipeptidyl peptidase-4 (CD26) inhibitor. CD26 activates serine proteases in immune/inflammatory cells. Vildagliptin also inhibits dipeptidyl-peptidase 8 (DPRP1) and dipeptidyl-peptidase 9 (DPRP2), which have been correlated to T cell activation and immune function, as well as diabetes and cancer regulation.A CD26 inhibitor associated with immune response inhibition Vildagliptin is a dipeptidyl peptidase-4 (CD26) inhibitor. CD26 activates serine proteases in immune/inflammatory cells. Vildagliptin also inhibits dipeptidyl-peptidase 8 (DPRP1) and dipeptidyl-peptidase 9 (DPRP2), which have been correlated to T cell activation and immune function, as well as diabetes and cancer regulation. A CD26 inhibitor associated with immune response inhibition
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Vildagliptin (LAF-237)
Dangerous GoodsCAS number:274901-16-5 molecular formula:C17H25N3O2
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Specs
| Chinese alias | 维达列汀 | 维他列汀 | ||
| English alias | (2S)-1-{2-[(3-Hydroxyadamant-1-yl)amino]acetyl}pyrrolidine-2-carbonitrile | (2S)-{((3-Hydroxyadamantan-1-yl)amino)acetyl}pyrrolidine-2-carbonitrile | (2S)-1-{[(3-hydroxyadamant-1-yl)amino]acetyl}pyrrolidine-2-carbonitrile | Vildagliptin | NSC-37389 | s303 | ||
| CAS number | 274901-16-5 | molecular formula | C17H25N3O2 |
| molecular weight | 303.4 g/mol | Exact mass | - |
| PSA | 76.400 Ų | logp | 0.9 |
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Safety information
Hazard Statement:
H413: 可能对水生生物造成长期的有害影响
Statement of Preventive Measures:
P273: 避免释放到环境中。 P501: 将内容物/容器处理到。。。
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