compound introduction
Avanafil is a highly selective PDE5 inhibitor with IC50 of 5.2 nM, >121-fold selectivity over other PDEs. Avanafil is a highly selective PDE5 inhibitor with IC50 of 5.2 nM, >121-fold selectivity over other PDEs.
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Avanafil
Dangerous GoodsCAS number：330784-47-9 molecular formula：C23H26ClN7O3
overview
Specs
| Chinese alias | 阿伐那非 | (S)-4-[(3-氯-4-甲氧基苄基)氨基]-2-[2-(羟甲基)吡咯烷-1-基]-N-(嘧啶-2-基甲基)嘧啶-5-甲酰胺 | 阿伐那菲 | ||
| English alias | 4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)-1-pyrrolidinyl)-n-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide | AVANAFIL [WHO-DD] | MFCD11977961 | TA1790 | TA-1790 | UNII-DR5S136IVO | (S)-4-[(3-Chlor-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)- | ||
| CAS number | 330784-47-9 | molecular formula | C23H26ClN7O3 |
| molecular weight | 483.95 g/mol | Exact mass | - |
| PSA | 125.000 Ų | logp | 2.6 |
numbering system
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physicochemical properties
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Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移
Production methods and uses
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MSDS
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