Sunitinib is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit.苹果酸舒尼替尼属于多靶点酪氨酸激酶抑制剂。 Sunitinib is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit.
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Sunitinib Malate
Dangerous GoodsCAS number:341031-54-7 molecular formula:C22H27FN4O2·C4H6O5
overview
compound introduction
Specs
| Chinese alias | 苹果酸苏尼替尼 | ||
| English alias | 1H-Pyrrole-3-carboxamide, N-(2-(diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-, (2S)-hydroxybutanedioate (1:1) | CAS-341031-54-7 | Sunitinib malate | (Z)-N-(2-(diethylamino)ethyl)-5-((5-fluoro-2-oxoindo | ||
| CAS number | 341031-54-7 | molecular formula | C22H27FN4O2·C4H6O5 |
| molecular weight | 532.56 g/mol | Exact mass | ≥99% |
| PSA | 172.000 Ų | logp | - |
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Safety information
pictogram:
GHS08
Signal word:
Danger
Hazard Statement:
H372: 通过长时间或反复暴露对器官造成损害 H360: 可能损害生育力或未出生的孩子
Statement of Preventive Measures:
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P203: 使用前,获取、阅读并遵守所有安全说明。 P318: 如果暴露或担心,请就医。 P319: 如果你感到不适,请寻求医疗帮助。
WGK Germany:
2
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