Eprotirome (KB2115) 是肝脏选择性甲状腺激素受体 (thyroid hormone receptor, TR) 激动剂。KB2115 对 TRβ 的亲和力略高于 TRα。Eprotirome 降低了低密度脂蛋白 (LDL) 胆固醇的浓度,可用于血脂异常和肥胖症的研究。 Information Eprotirome (KB2115) Eprotirome (KB2115) is a liver-selective agonist of thyroid hormone receptor (TR) . Eprotirome is investigated for the potential treatment of dyslipidemias and obesity. Targets THR
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Eprotirome (KB2115)
Dangerous GoodsCAS number:355129-15-6 molecular formula:C18H17Br2NO5
overview
compound introduction
Specs
| Chinese alias | 伊罗替罗 (KB2115) | 埃普罗替罗姆 (KB2115) | ||
| English alias | DTXSID10319332 | 3-((3,5-DIBROMO-4-(4-HYDROXY-3-(PROPAN-2-YL)PHENOXY)PHENYL)AMINO)-3-OXOPROPANOIC ACID | SCHEMBL759034 | D82452 | BDBM50385105 | 3-((3,5-Dibromo-4-(4-hydroxy-3-(1-methylethyl)phenoxy)phenyl)amino)-3-oxopropanoic acid | EPROTIROME [MI] | 3- | ||
| CAS number | 355129-15-6 | molecular formula | C18H17Br2NO5 |
| molecular weight | 487.14 g/mol | Exact mass | ≥98% |
| PSA | 95.900 Ų | logp | 5 |
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physicochemical properties
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Safety information
pictogram:
GHS07
Signal word:
Warning
Hazard Statement:
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
Statement of Preventive Measures:
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
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