CAS number：376348-65-1 molecular formula：C29H41F2N5O
Maraviroc (UK-427857)是一种CCR5拮抗剂，作用于MIP-1α，MIP-1β和RANTES，无细胞试验中IC50分别为3.3 nM，7.2 nM和5.2 nM。Maraviroc可应用于治疗HIV感染。 Maraviroc has been used as a C-C chemokine receptor type 5 (CCR5-specific) inhibitor in murine monocyte/macrophage cell line J774A.1, porcine uterine luminal epithelial cells and human lung CD4+ T cells.
| Chinese alias | 4,4-二氟-N-(1S)-3-(3-外)-3-3-甲基-5-(1-甲基乙基)-4H-1,2,4-三唑-4-基-8-氮杂双环 | 3.2.1 辛-8-基-1-苯基丙基 环己甲酰胺 | 马拉韦罗 | 马拉维若 | ||
| English alias | UK-427857 | ||
| CAS number | 376348-65-1 | molecular formula | C29H41F2N5O |
| molecular weight | 513.67 g/mol | Exact mass | - |
| PSA | 63.100 Ų | logp | 5.1 |
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