CAS number：379231-04-6 molecular formula：C27H32ClN5O5
Saracatinib (AZD0530)是一种有效的Src抑制剂，IC50为2.7 nM，对c-Yes， Fyn， Lyn， Blk， Fgr和Lck等也有活性；但对Abl和EGFR (L858R和L861Q)活性较低。Phase 2/3。 Saracatinib (AZD0530) is a potent Src inhibitor with IC50 of 2.7 nM, and potent to c-Yes, Fyn, Lyn, Blk, Fgr and Lck; less active for Abl and EGFR (L858R and L861Q). Phase 2/3. A diverse Src inhibitor.
| Chinese alias | 塞卡替尼 | 萨拉替尼(AZD0530) | ||
| English alias | HMS3265E22 | SCHEMBL41547 | BRD-K19540840-001-05-2 | AZ-10353926 | MFCD09832698 | SB16503 | NSC735464 | AS-16692 | HMS3265E21 | EX-A1576 | 4-(6-chloro-2,3-methylenedioxyanilino)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-tetrahydropyran-4-yloxyquinazoline | H | ||
| CAS number | 379231-04-6 | molecular formula | C27H32ClN5O5 |
| molecular weight | 542.03 g/mol | Exact mass | - |
| PSA | 90.400 Ų | logp | 4.1 |
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