CAS number：404844-11-7 molecular formula：C24H20ClN5O
PDGFRα kinase inhibitor 2 (compound 1) 是一种伊马替尼 (HY-15463) 类似物，是一种共价不可逆激酶抑制剂，对于 ABL1 wt、KIT wt、PDGFRR wt 的 IC50 分别为 6.95 μM、2.45 μM、1.39 μM。 PDGFRα kinase inhibitor 2 (compound 1), an Imatinib (HY-15463) analogue, is a covalent and irreversible kinase inhibitor with IC50s of 6.95 μM, 2.45 μM, 1.39 μM for ABL1 wt, KIT wt, PDGFRR wt.
| Chinese alias | 伊马替尼杂质3 | 4-(氯甲基)-N-(4-甲基-3-((4-(吡啶-3-基)嘧啶-2-基)氨基)苯基)苯甲酰胺 | ||
| English alias | PD119309 | 4-(chloromethyl)-N-{4-methyl-3-[4-(pyridin-3-yl)pyrimidin-2-ylamino]phenyl}benzamide | n-(5-(4-chloromethylbenzoylamino)-2-methylphenyl)-4-(3-pyridyl)-2-pyrimdine-amine | Chloromethyl-N-[4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]Amino]phenyl] | ||
| CAS number | 404844-11-7 | molecular formula | C24H20ClN5O |
| molecular weight | 429.90 g/mol | Exact mass | - |
| PSA | 79.800 Ų | logp | 4.3 |
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