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rilapladib

CAS number:412950-08-4    molecular formula:C40H38F5N3O3S

overview

compound introduction

Rilapladib (SB 659032) 是脂蛋白相关磷脂酶 A2 (Lp-PLA2) 的一个选择性抑制剂,IC50 值为 230 pM。Rilapladib (SB 659032) 也是血小板活化因子受体 (PAFR) 的拮抗剂。 Rilapladib (SB 659032) is a selective Lp-PLA2 (lipoprotein-associated phospholipase A2) inhibitor with an IC50 of 230 pM. Rilapladib (SB 659032) is also a PAFR (Platelet Activating Factor Receptor) antagonist.

Specs

Chinese alias瑞拉帕地
English alias2-[[(2,3-Difluorophenyl)methyl]thio]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1(4H)-quinolineacetamide | BDBM50205805 | Q27088554 | COTARNINE CHLORIDE [MI] | O14CWE893Z | SB-659032; SB659032; SB 65903
CAS number412950-08-4molecular formulaC40H38F5N3O3S
molecular weight735.8 g/molExact mass-
PSA78.400 Ųlogp8.1

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