Vandetanib

Dangerous Goods

CAS number：443913-73-3 molecular formula：C22H24BrFN4O2

overview

Specs

numbering system

physicochemical properties

Safety information

Production methods and uses

MSDS

overview

compound introduction

Vandetanib is an antagonist of VEGFR (Flk and Flk) and EGFR families. Specifically inhibits kinase activity of Flk-1. Vandetanib is an inhibitor of Flt-4.An antagonist of VEGFR (Flk and Flk) and EGFR families. Vandetanib is an antagonist of VEGFR (Flk and Flk) and EGFR families. Specifically inhibits kinase activity of Flk-1. Vandetanib is an inhibitor of Flt-4. An antagonist of VEGFR (Flk and Flk) and EGFR families.

Specs

Chinese alias	凡德他尼
English alias	ZD6474 \| N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine \| N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
CAS number	443913-73-3	molecular formula	C22H24BrFN4O2
molecular weight	475.36 g/mol	Exact mass	-
PSA	59.500 Å²	logp	4.900

numbering system

No numbering system information yet

physicochemical properties

No physical and chemical property information yet

Safety information

pictogram：

GHS08 , GHS09 , GHS07

Signal word：

Danger

Hazard Statement：

H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H373: 通过长时间或反复暴露对器官造成损害 H302: 吞食有害 H400: 对水生生物有剧毒 H410: 对水生生物有剧毒并具有长期持续影响 H360: 可能损害生育力或未出生的孩子 H360Df: 可能会伤害未出生的孩子；怀疑破坏生育力

Statement of Preventive Measures：

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾