compound introduction
Alvespimycin (17-DMAG; KOS-1022; NSC 707545)是水溶性HSP90抑制剂，IC50为62 nM。A synthetic Geldanamycin derivative and inhibitor of Hsp90. A synthetic Geldanamycin derivative and inhibitor of Hsp90.
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Alvespimycin
CAS number：467214-20-6 molecular formula：C32H48N4O8
overview
Specs
| Chinese alias | 阿螺旋霉素 | ||
| English alias | NSC 707545 | (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-{[2-(dimethylamino)ethyl]amino}-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate | 17-DMAG | ((4E,6Z,8S,9S,10E,12S,13R,14S,1 | ||
| CAS number | 467214-20-6 | molecular formula | C32H48N4O8 |
| molecular weight | 616.75 g/mol | Exact mass | - |
| PSA | 170.000 Ų | logp | 2.000 |
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