Sitagliptin 是一种有效的 DPP4 抑制剂,在 Caco-2 细胞中,IC50 值为 19 nM。
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sitagliptin
Dangerous GoodsCAS number:486460-32-6 molecular formula:C16H15F6N5O
overview
compound introduction
Specs
| Chinese alias | 西他列汀 | 西他列汀 | ||
| English alias | MK-0431 | (3R)-3-amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one | 1,2,4-TRIAZOLO(4,3-A)PYRAZINE-7(8H)-PROPANAMINE, 5,6-DIHYDRO-gamma-OXO-3-(TRIFLUOROMETHYL)-alpha-((2,4,5-TRIFLUOROPHENY | ||
| CAS number | 486460-32-6 | molecular formula | C16H15F6N5O |
| molecular weight | 407.3136 g/mol | Exact mass | - |
| PSA | 77.000 Ų | logp | 0.700 |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS08 , GHS07
Signal word:
Danger
Hazard Statement:
H319: 引起严重眼睛刺激 H373: 通过长时间或反复暴露对器官造成损害
Statement of Preventive Measures:
P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P501: 将内容物/容器处理到。。。
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MSDS
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