CAS number：496775-61-2 molecular formula：C25H22N4O4
Eltrombopag 是小分子，c-mpl (TpoR) 受体激动剂，抑制 hERG K+通道尾电流，IC50为0.69 μM。 Eltrombopag is a member of the biarylhydrazone class, which is a nonpeptide agonist of the thrombopoietin receptor (TpoR). An agonist of the thrombopoietin receptor
| Chinese alias | 伊屈泼帕 | (Z)-3'-[2-[1-(3,4-二甲基苯基)-3-甲基-5-氧代-1,5-二氢-4H-吡唑-4-亚基]肼基]-2'-羟基-(1,1'-联苯)-3-甲酸 | 3'-[(2Z)-2-[1-(3,4-二甲基苯基)-3-甲基-5-氧代-1,5-二氢-4H-吡唑-4-亚基]肼基]-2'-羟基(联苯)-3-甲酸 | ||
| English alias | BCP9000641 | D02363 | CHEBI:85010 | EN300-1709152 | XDXWLKQMMKQXPV-UHFFFAOYSA-N | SB497115 | SB-497115 | 3'-[(2Z)- [1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid | 3'-{2-[1-( | ||
| CAS number | 496775-61-2 | molecular formula | C25H22N4O4 |
| molecular weight | 442.47 g/mol | Exact mass | - |
| PSA | 115.000 Ų | logp | 5.400 |
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