Sunitinib is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit. Sunitinib is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit.
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Sunitinib
Dangerous GoodsCAS number:557795-19-4 molecular formula:C22H27FN4O2
overview
compound introduction
Specs
| Chinese alias | 舒尼替尼 | ||
| English alias | 1H-Pyrrole-3-carboxamide,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl- | D08552 | C22H27FN4O2 | N-(2-(Diethylamino)ethyl)-5-((Z)-(5-fluoro-1 pound not2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2 pound not4-dimethyl-1H-pyrrole-3-carboxamide | SC | ||
| CAS number | 557795-19-4 | molecular formula | C22H27FN4O2 |
| molecular weight | 398.47 g/mol | Exact mass | - |
| PSA | 77.200 Ų | logp | 2.600 |
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physicochemical properties
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Safety information
pictogram:
GHS06
Signal word:
Danger
Hazard Statement:
H372: 通过长时间或反复暴露对器官造成损害 H360: 可能损害生育力或未出生的孩子
Statement of Preventive Measures:
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P201: 使用前获取特殊说明 P308+P313: 如接触到或有疑虑:求医/就诊。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P202: 在阅读并理解所有安全预防措施之前,不要进行操作。
UN Number:
2811
Packing Group:
III
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