2-二环己基磷-2',4',6'-三异丙基联苯是一种由Buchwald集团开发的空气稳定的富电子联芳基单膦配体2，以增强在交叉偶联反应过程中提高钯催化的反应性。 1、用于深入研究芳烃磺酸酯、芳基卤的钯催化胺化和酰胺化反应的配体； 2、用作钯催化 Suzuki 偶联反应的配体，生成文朵灵的 C-15 类似物； 3、用于钯催化 2-卤代苯胺直接环化生成吲哚和色氨酸。区域规则性聚噻吩的合成。 It is a ligand for increased scope of Pd-catalyzed amination and amidation via arene sulfonates, aryl halides. It is a ligand used in a Pd-catalyzed Suzuki coupling leading to C-15 analogs of vindoline and direct annulation of 2-haloanilines to indoles and tryptophans. Preferred ligand for greener Sonogashira coupling in TPGS-750-M. It may be used as a ligand in the following reactions: • Preparation of functionalized benzylic sulfones via palladium-catalyzed Negishi cross-coupling between alkyl sulfones and aryl halides. • Along with pre-milled palladium(II) acetate as a pre-catalyst for the Stille cross-coupling of aryl chlorides with tributylarylstannanes to form the corresponding biaryl compounds. •Along with platinum chloride to catalyze the hydrosilylation of terminal arylalkynes with silanes to form functionalized β-(E)-vinylsilanes
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2-Dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl
Dangerous GoodsCAS number：564483-18-7 molecular formula：C33H49P
overview
compound introduction
Specs
| Chinese alias | 2-双环己基膦-2',4',6'-三异丙基联苯 | 二环己基(2',4',6'-三异丙基-[1,1'-联苯]-2-基)膦 | 2-二环己基膦-2',4',6'-三异丙基联苯 | ||
| English alias | dicyclohexyl (2',4',6'-triisopropyl-[1,1'-biphenyl]-2-yl)phosphine | dicyclohexyl[2',4',6'-tris(propan-2-yl)-[1,1'-biphenyl]-2-yl]phosphane | dicyclohexylphosphino-2',4',6'-triisopropyl-1,1'-biphenyl | 2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRI-I-PROPYL-1,1'-BI | ||
| CAS number | 564483-18-7 | molecular formula | C33H49P |
| molecular weight | 476.72 g/mol | Exact mass | ≥97% |
| PSA | 0.000 Ų | logp | 10.100 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
pictogram：
GHS07
Signal word：
Warning
Hazard Statement：
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H413: 可能对水生生物造成长期的有害影响 H302: 吞食有害
Statement of Preventive Measures：
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P270
WGK Germany：
3
Personal protective equipment：
Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter
Production methods and uses
No production method and use information yet
Related
upstream information
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downstream information
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MSDS
Found 1 shareMSDS
564483-18-7 | XPhos.pdf
