Obatoclax Mesylate (GX15-070)是一种Bcl-2拮抗剂,Ki为0.22 μM,可以协助性的抑制MCL-1介导的抗细胞凋亡作用。Phase 3。A novel Bcl-2 homology domain-3 (BH3) mimetic. Obatoclax (GX15-070) is an antagonist of Bcl-2 with Ki of 0.22 μM, can assist in overcoming MCL-1 mediated resistance to apoptosis. Phase 3. A novel Bcl-2 homology domain-3 (BH3) mimetic.
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Obatoclax Mesylate
Dangerous GoodsCAS number:803712-79-0 molecular formula:C20H19N3O.CH4O3S
overview
compound introduction
Specs
| Chinese alias | Obatoclax 甲磺酸盐 | ||
| English alias | Ethyl beta-D-glucopyranosiduronate | 2-(2-((3,5-DIMETHYL-1H-PYRROL-2-YL)METHYLIDENE)-3-METHOXY-2H-PYRROL-5-YL)-1H-INDOLE MONOMETHANESULPHONATE | 3-Carboxy-2,5-dimethyl-1H-pyrrol-2-ylmethylene)-5-(1H-indol-2-yl)-3-methoxy-2H-pyrrolium, mesylate salt | Obat | ||
| CAS number | 803712-79-0 | molecular formula | C20H19N3O.CH4O3S |
| molecular weight | 413.5 g/mol | Exact mass | ≥97% |
| PSA | 112.000 Ų | logp | - |
numbering system
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physicochemical properties
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Safety information
pictogram:
GHS06 , GHS07
Signal word:
Danger
Hazard Statement:
H315: 引起皮肤刺激 H301: 吞咽会中毒
Statement of Preventive Measures:
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染:用水充分清洗。 P321: 特殊处理(请参阅此标签上的...)。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P362+P364: 脱掉沾污的衣服,清洗后方可重新使用。 P330: 漱口 P301+P316: 如果吞咽:立即寻求紧急医疗救助。 P332+P317: 如果出现皮肤刺激:请寻求医疗帮助。
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MSDS
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